Young George mixes a medicine to make his nasty grandmother more likeable, and once she drinks it she grows to immense proportions. George's father wants the formula to breed a race of super-size livestock, but George can't duplicate the recipe. His fourth try is a potion that shrinks the drinker to nothing - and greedy Grandma drinks it with expected results.
Most grandmas are kind and helpful ladies. Not George's grandma. She's a grumpy and grizzly old grouch and George wants to teach her a lesson. So when it's time for her medicine, George concocts a bubbling, frothing, marvellous mixture, which is guaranteed to send her through the roof . . .